Abstract: To effectively control environmental quality of livestock and poultry houses and purify air，a technical measure for environmental control of livestock and poultry houses was introduced based on anti-epidemic and disease prevention technology of air electric purification.Results showed that dust removal rate of enclosed pig house was 70%，and bacterial rate was maintained at 50%.Electric air purification and epidemic prevention measures could effectively reduce dust and air microorganisms in livestock and poultry environment，control environmental quality of livestock and poultry houses，purify air and achieve purpose of epidemic prevention.This research provides a method of eliminating harmful microorganisms with high application value.