Abstract: Impact of industrial organization optimization on agricultural economic growth is a topic of common concern of relevant scholars and experts.In view of this phenomenon，based on analysis of current situation of industrial structure and economic growth in the central region，two indicators of Theil index and Moore structure change value were introduced，the least square regression model was constructed to analyze impact of industrial structure optimization on agricultural economy.Model performance was verified through three major methods：stationarity test，cointegration test and Granger causality test.D（LnY）and D（M），D（LnY）and D（TL）had no unit roots after first-order treatment，and time variables were stationary.Rationalization of industrial structure and economic development were mutually causal，and upgrading of industrial structure and economic development were also causality.Their regression equations and resolvable coefficients of model were 97% and 98% respectively.