Abstract: Low mechanization of cassava production is one of bottlenecks restricting development of cassava industry in China．Research on high-performance cassava precision planter plays an important role in promoting stable development of cassava industry．Structure of cassava precision planter is complex．In order to improve working performance, frame of automatic seed metering device must have good structure and mechanical properties．Frame of double row cassava planter uniform precision automatic seed metering device developed by research group was taken as research object, finite element model of frame was established by UG and ANSYS software, and static analysis, constrained modal analysis and sensitivity analysis of frame of automatic seed metering device were carried out by ANSYS Work Bench．Optimization response was determined by modal analysis, design variables were determined by sensitivity analysis, optimization objectives were determined by model establishment, and six groups of non-inferior solutions were obtained by multi-objective optimization design mathematical model calculation．Among the six schemes and initial schemes, optimal frame structure scheme was selected based on fuzzy matter-element model of entropy weight．Comparative analysis before and after frame optimization of uniform precision automatic seed metering device of double row cassava planter showed that the first modal frequency was increased by 3.60%, frame mass was reduced by 8.76%, and the maximum deformation was reduced by 5.08%, which better achieved purpose of lightweight structure optimization of frame．Research results could provide a reference for design and optimization of cassava precision planter．