Abstract: To evaluate ecological adaptability of eight new flue-cured tobacco varieties in Bijie tobacco-growing areas, taking Yunyan 87 as control variety, differences in growth period, agronomic traits, economic traits, appearance quality, chemical composition and sensory quality of tested varieties were studied, and comprehensive evaluation of tested varieties was carried out by TOPSIS method．Results showed that field development stage of 40122, ZY211, MT-7, and GY2107 was longer, and agronomic traits were better．Yield of 9394 was the highest, followed by ZY211, MT-7, and 40122．Average price of ZY211 was the highest, followed by 40122．Output value and high-grade tobacco rate of ZY211 were the highest, followed by 9394 and 40122, and high and medium grade tobacco rate of 40122 was the highest．Appearance quality score of A1（ 8016 ）was better than that of control variety．Nitrogen-alkali ratio and potassium-chlorine ratio of each variety were suitable, and sugar-alkali ratio of 9394 was suitable, and comprehensive score was the highest．Scores of aroma quality, offensive odor, irritation, and aftertaste of A1（ 8016 ）and 40122 were higher than those of control variety, and aroma content of A1（ 8016 ）was higher than that of control variety, and comprehensive score was the highest．The top three in comprehensive evaluation were 40122, A1（8016）, and Yunyan 87．40122 and A1（ 8016 ）had better comprehensive performances and strong adaptability, to be further demonstrated and verified．