Abstract: Based on annual regional drought evaluation index（MCI_e）, DEM data, topographic slope data, population density, GDP, river network density, NDVI , irrigation farmland distribution, crop planting distribution, and other data, drought disaster risk assessment and regionalization research of Heng-Shao drought corridor was carried out．Results showed that high risk regions for drought disaster in Heng-Shao drought corridor were mainly distributed in east-central regions, among which Hengdong County, Hengshan County, Hengnan County, Hengyang County, Leiyang City, Qidong County, Qiyang County, Dong'an County, Lengshuitan District of Yongzhou City, Shaodong City and Shuangfeng County of Hunan Province had a higher risk of drought．Xinning County, Suining County, and Chengbu Miao Autonomous County had a lower risk of drought, and other regions had a medium risk．Precision regionalization of drought disaster risk in Heng-Shao drought corridor has important guiding significance for improving level of drought disaster risk management and meteorological disaster prevention and mitigation in region．