Abstract: On the basis of the biomutagenic effect motivated by electromagnetic spectrum，new physical control methods of disease，pests and weeds in agriculture were discussed.Laser irradiation test verifies the activity depressing and even death of insect radiated，and a power density threshold of laser radiation to kill insect was obtained，whereby laser insect killer with large emitting area and high radiating power density was designed using a method of laser diode arraying integration.The spectral sensitivity of locust phototaxis trapping was excited through a suitable design for LED arraying integration and stroboscopic luminescence control，and further 85% capturing rate to locust was attained in the test of photoelectronic trapping machine with slipping funnel configuration.A higher temperature rising and even hot burning death of weeds were realized by laser irradiation killer，and the hydraulic driving system of cylindrical coordination machinery arm for manipulating laser killer as well as its carrying traveling unit in cultivated land was devised，so in which a optoelectronic mechanization technology of laser weed control was constituted.