Abstract: A method for determining 5 preservatives and 2 sweeteners by HPLC was studied.The sample was extracted and separated in C18 column，and tested by DAD detector.According to experimental results，7 additives were completely separated，and the method showed a good linearity，average recovery rate varied from 87.7% to 105.0%，with relative standard deviations between 1.21% and 4.72%.Thanks to its simplicity，rapidity，accuracy and low limit of detection，this method will have a promising application for analyzing real samples.