Abstract: In order to solve problem of increasing feeding scale and quantity of laying hens，increasing epidemic disease，increasing dosage and decrease of eggs quality，physical technical environment control and prevention mode was implemented to scale breeding laying hens.It could significantly reduce occurrence of layer disease.Henhouses air quality was improved significantly.PM10 index reduced by 50%，the PM2.5 index decreased by 60%，NH3 content reduced by 80%，SO2 content reduced by 70%，and egg laying amount increased 2.3%.It has important significance for popularization.