Abstract: Efficiency of scientific and technological research and development in Jilin province during 12th Five-year Plan period were studied by using data envelopment model（DEA）analysis method.Research showed that efficiency of science and technology research and development in Jilin province was higher than that of results，and efficiency of each city state was significantly different.Degree of economic evelopment has no significant impact on efficiency of science and technology research and development，and quantity and quality of colleges and universities were of great significance to them.According to the value of R & D innovation and transformation efficiency，R & D activity pattern of nine cities was divided into four modes：high innovation and high transformation，high innovation and low transformation，low innovation and high conversion，low innovation and low transformation.Jilin province R & D innovation and transformation efficiency focus mainly on the future mining matsubara and baishan region，secri should be to promote the development of scientific and technological achievements transformation as an opportunity to take effective measures to speed up the transformation of scientific and technological innovation of process.