Abstract: Existing production practice of agricultural mechanization and automation major have persistent challenges that expand the coverage of internships，enhance professional skills，and enrich teaching practices to achieve goal of excellent engineer education training objectives and new engineering talent training requirements，highlighting a need for teaching reform and practice.The purpose of teaching research was to establish specific measures for reforming teaching contents and teaching methods for production practice of major.A framework of practical teaching with integration of research and education and professional characteristics was set up，which took advantage of superior resources of school-enterprise cooperation in field of agricultural machinery development of Huazhong Agricultural University.Practice content was considerately organized as series professional skills modules according to production process of the company′s main product which was a precision combined seeder innovated by the university.Student-centered teaching process was developed as well as combining theory with practice according to characteristics of practical learning.Practical result has proved that teaching reform guarantees depth of practical teaching，strengthens features and breadth of professional practice，and enhances students′ initiative and enthusiasm for participating in practical activities.It combines engineering practice with theory and lays a solid foundation for follow-up study and work.The research demonstrated a reference for reform production practice teaching for agricultural mechanization and automation major.