Abstract: In order to solve problem of high impurity rate of Cerasus humilis after operation of Cerasus humilis harvesting unit，a kind of air screen cleaning device for Cerasus humilis was designed.With coupling method of EDEM-Fluent，cleaning process was simulated and analyzed by taking vibration amplitude，frequency and wind speed as experimental factors，cleaning rate and loss rate of Cerasus humilis as evaluation indexes，and cleaning device were tested according to simulation results.Simulation analysis and bench test showed that with increase of wind speed，vibration frequency and amplitude，cleaning rate of Cerasus humilis firstly increased but then decreased，and loss rate always increased.Optimal operating parameter combination was wind speed 10 m/s，amplitude 10 mm and vibration frequency 9 Hz.Under optimal operating parameter combination，cleaning rate of Cerasus humilis was 96.3%，and loss rate was 3.4%.Study indicated that application of EDEM-Fluent coupling simulation was helpful to research of Cerasus humilis cleaning.Study results could provide a theoretical basis for design and optimization of device for Cerasus humilis cleaning.