Abstract: In order to evaluate pollution status of antibiotics in soil of vegetable bases in Yangling District，contents of 19 antibiotics in 4 categories of quinolones，tetracyclines，sulfonamides and macrolides in soil samples from 20 bases were detected and analyzed.Results showed that，quinolones，sulfonamides and tetracyclines were all detected in 100% of soil samples，and detection rate of macrolides was 62%.The average contents of four antibiotics from high to low were quinolones（51.76 μg/kg）>tetracyclines（12.77 μg/kg）>sulfonamides（1.14 μg/kg）>macrolides（0.28 μg/kg），and norfloxacin，oxytetracycline，sulfamethazine and erythromycin were the main contents，respectively.According to trigger value of ecological toxic effect of antibiotics in soil（100 μg/kg）proposed by the Steering Committee of the International Coordinating Committee for Veterinary Medicine（VICH），contents of four classes of antibiotics in soil of study area were all lower than trigger value，indicating a small ecological risk.Compared with other domestic research reports，vegetable bases in this study area were also at a relatively low level of antibiotic pollution.