Abstract: Maifan stone and ceramsite particles were used as substrates for soilless culture and aquaculture water filtration in fish vegetable symbiosis system respectively.Plant height，root length，aboveground fresh weight and chlorophyll content of lettuce，survival rate，weight gain rate of snakehead，and pH value，dissolved oxygen content of water quality were measured.Test results showed that growth and development of lettuce and snakehead could be improved by adding maifan stone in fish vegetable symbiosis system.Compared with control group，root length，plant height，weight and chlorophyll content of test group increased by 18-4%，15-0%，21-9% and 45-8% respectively.In the process of snakehead culture，compared with control group，pH increased by 0-42，dissolved oxygen content by 0-69 mg/L，mortality reduced by 7-6%，and weight gain increased by 23-68% of test group.Test proofed that maifan stone was stable in fish vegetable symbiosis system，and had good effect on growth and development of vegetables and snakehead，and water conservation.