Abstract: In order to address issues of excessive spray boom in large-scale high clearance sprayer and poor damping effect of vibration damping elements, using test method of quadratic orthogonal rotation combination, field vibration tests with four factors and three levels were carried out on suspension damping elements, and significance and trend of each factor's influence on vibration were obtained．Parameters of vibration damping combinations were optimized and experimentally validated．The optimal vibration damping combination was found to be a sprayer travel speed of 2.125 m/s, a vertical spring stiffness coefficient of 78.14 N/mm, a vertical damper restoring damping coefficient of 8.23 N·s/mm, and a horizontal damper restoring damping coefficient of 8.74 N·s/mm．After optimization, percentage of acceleration within the range of 0～6 m/s² in the boom's direction of travel accounted for 85.26%, which was increased by more than 4%．Percentage within range of 0～0.6° for roll angle accounted for 88.37%, which was increased by more than 4%．And percentage within range of 0～6 m/s² for vertical direction acceleration accounted for 87.96%, which was increased by more than 3%．Combination testing and optimization validation of boom suspension vibration damping elements could provide valuable references for setting operational parameters and selecting damping element parameters for sprayers．