Abstract: In order to solve problems of chaotic instrument and equipment borrowing, cumbersome management work, and untimely communication between administrators and teachers and students in current laboratory, and to accelerate informationization process of laboratory management, a laboratory information management system was designed and developed based on SSH framework and Java as development language, MySQL as system database, through in-depth research and analysis of college laboratory．The system was designed to cater to different user needs by setting up three user roles, namely laboratory administrator, teacher, and student, to assign corresponding permissions according to roles．It could achieve functions such as administrator user review, laboratory and instrument appointment, laboratory equipment repair, and laboratory equipment information management．The system has a user-friendly interface, simple operation, and strong practicality, which could effectively alleviate work pressure of management personnel, improve laboratory management and utilization efficiency, and meet needs of daily laboratory management．