Abstract: Science and technology is the key driver of rural revitalization．Meanwhile, scientific research institute is an important force for rural revitalization．However, there are many problems in practice, such as unsustainable methods, poorly targeted projects and low conversion rate of results．Taking Guangxi Institute of Meteorological Sciences as an example, a case study method was adopted to explore and analyze innovative practice process and content of assisting rural revitalization from multiple dimensions．Based on this, basic path of technology assisted rural revitalization strategy was proposed, aiming to provide theoretical guidance and experience reference for technology departments to assist rural revitalization strategy．