Abstract: The purpose of this study was to evaluate contents of heavy metals in soil and wheat around typical pollution sources and possible risks to human health, so as to provide scientific basis for soil remediation and crop safety．Study area was selected in the northern plain of Henan Province．Main soil type was yellow cinnamon soil, and wheat was main food crop．Research objects were soil and wheat around highways, landfills and key heavy metal enterprises．Plum blossom point method was used to collect 0 to 20 cm soil samples on surface．Soil samples were air-dried, crushed and screened to prepare samples with different particle sizes．Content of heavy metals in soil was analyzed by atomic fluorescence spectrometer and X-ray fluorescence spectrometer, and soil pH and cation exchange capacity were determined according to national standard method respectively．Health risk assessment adopted method of EPA, taking into account physical function of adults and minors, and health risk of heavy metals was evaluated through three ways: hand-mouth intake, respiratory intake and skin contact intake．Risk assessment included calculation of non-carcinogenic risk index（HI）and carcinogenic risk index（CR）．Results showed that except As, contents of Hg, Pb, Cd, Cr, Cu, Zn and Ni were higher than soil background values in Henan Province．The non-carcinogenic risk index of adults and children showed that non-carcinogenic risk was within acceptable range, but it should be alert to accumulation of Cd．Carcinogenic risk index showed that carcinogenic risk of soil in study area to adults and children was also within acceptable range．Content of heavy metals in soil of study area was higher than background value as a whole, and some sites had safety risks, which need to be paid attention．Although current non-carcinogenic and carcinogenic risks faced by adults and children were within acceptable range, preventive measures were recommended．